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1

Aligning needs

Ford, Dennis, Kohlbrenner, William

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 493 KB

english, 2016

2

Cefixime vs. cefaclor in the treatment of acute otitis media in children

RODRIGUEZ, WILLIAM J., KHAN, WAHEED, SAIT, TAHIR, CHHABRA, OM P., BELL, THOMAS A., AKRAM, SHAMA, KOHLBRENNER, VERONIKA M.

Journal:

Pediatric Infectious Disease Journal

Year:

1993

File:

PDF, 708 KB

1993

3

Pharmacodynamics and pharmacokinetics of the methyl ester of 15-deoxy-16-hydroxy-16-vinylprostaglandin E2

Vijay K. Batra, John A. Morrison, Donna B. Cosulich, William Dougherty, Nancy Perkinson, Michael Kohlbrenner, Andrew Barr, Avraham Yacobi

Journal:

Journal of Pharmaceutical Sciences

Year:

1985

Language:

english

File:

PDF, 220 KB

english, 1985

4

Use of a Fluorescence Plate Reader for Measuring Kinetic Parameters with Inner Filter Effect Correction

Yaya Liu, Warren Kati, Chih-Ming Chen, Rakesh Tripathi, Akhter Molla, William Kohlbrenner

Journal:

Analytical Biochemistry

Year:

1999

Language:

english

File:

PDF, 70 KB

english, 1999

5

Synthesis of potent pyrrolidine influenza neuraminidase inhibitors

A. Chris Krueger, Yibo Xu, Warren M. Kati, Dale J. Kempf, Clarence J. Maring, Keith F. McDaniel, Akhteruzzaman Molla, Debra Montgomery, William E. Kohlbrenner

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 135 KB

english, 2008

6

Hepatitis C NS5B polymerase inhibitors: 4,4-Dialkyl-1-hydroxy-3-oxo-3,4-dihydronaphthalene-3-yl benzothiadiazine derivatives

Douglas K. Hutchinson, Teresa Rosenberg, Larry L. Klein, Todd D. Bosse, Daniel P. Larson, Wenping He, Wen W. Jiang, Warren M. Kati, William E. Kohlbrenner, Yaya Liu, Sherie V. Masse, Tim Middleton, Ak

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

7

Evolving therapeutic paradigms for HIV and HCV

Akhteruzzaman Molla, William Kohlbrenner

Journal:

Current Opinion in Biotechnology

Year:

2003

Language:

english

File:

PDF, 133 KB

english, 2003

8

Interconversion rates of tautomers of 3-deoxy-d-manno-octulosonic acid (KDO) from a quantitative analysis of two-dimensional n.m.r. exchange data

Stephen W. Fesik, William E. Kohlbrenner, Robert T. Gampe Jr., Edward T. Olejniczak

Journal:

Carbohydrate Research

Year:

1986

Language:

english

File:

PDF, 288 KB

english, 1986

9

Design of orally bioavailable, symmetry-based inhibitors of HIV protease

Dale J. Kempf, Kennan C. Marsh, Lynnmarie Codacovi Fino, Pamela Bryant, Adrienne Craig-Kennard, Hing L. Sham, Chen Zhao, Sudthida Vasavanonda, William E. Kohlbrenner, Norman E. Wideburg, Ayda Saldivar

Journal:

Bioorganic & Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.51 MB

english, 1994

10

High-level expression and purification of mature HIV-1 protease inEscherichia coliunder control of thearaBADpromoter

Alison Taylor, David P. Brown, Sunil Kadam, Mary Maus, William E. Kohlbrenner, Debra Weigl, Mary C. Turon, Leonard Katz

Journal:

Applied Microbiology and Biotechnology

Year:

1992

Language:

english

File:

PDF, 1.00 MB

english, 1992

11

Using three-dimensional substructure searching to identify novel, non-peptidic inhibitors of HIV-1 protease

Mark G. Bures, Charles W. Hutchins, Mary Maus, William Kohlbrenner, Sunil Kadam, John W. Erickson

Journal:

Tetrahedron Computer Methodology

Year:

1990

Language:

english

File:

PDF, 539 KB

english, 1990

12

Antibacterial agents specifically inhibiting lipopolysaccharide synthesis

Goldman, Robert, Kohlbrenner, William, Lartey, Paul, Pernet, Andre

Journal:

Year:

1987

File:

PDF, 462 KB

1987

13

Synthesis of (2S,5S,4R)-2,5-diamino-3,3-difluoro-1,6-diphenylhydroxyhexane: the core unit of a potent HIV proteinase inhibitor

Sham, Hing L., Wideburg, Norman E., Spanton, Stephen G., Kohlbrenner, William E., Betebenner, David. A., Kempf, Dale J., Norbeck, Daniel W., Plattner, Jacob J., Erickson, John W.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1991

Language:

english

File:

PDF, 222 KB

english, 1991

14

Symmetry-based inhibitors of HIV protease. Structure-activity studies of acylated 2,4-diamino-1,5-diphenyl-3-hydroxypentane and 2,5-diamino-1,6-diphenylhexane-3,4-diol

Kempf, Dale J., Codacovi, Lynnmarie, Wang, Xiu Chun, Kohlbrenner, William E., Wideburg, Norman E., Saldivar, Ayda, Vasavanonda, Sudthida, Marsh, Kennan C., Bryant, Pamela

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.46 MB

english, 1993

15

Human Serum Attenuates the Activity of Protease Inhibitors toward Wild-Type and Mutant Human Immunodeficiency Virus

Akhteruzzaman Molla, Sudthida Vasavanonda, Gondi Kumar, Hing L. Sham, Marianne Johnson, Brian Grabowski, Jon F. Denissen, William Kohlbrenner, Jacob J. Plattner, John M. Leonard, Daniel W. Norbeck, Da

Journal:

Year:

1998

Language:

english

File:

PDF, 95 KB

english, 1998

16

Inhibition of human immunodeficiency virus type I integrase by naphthamidines and 2-aminobenzimidazoles

Tim Middleton, Hock B. Lim, Debra Montgomery, Todd Rockway, Hua Tang, Xueheng Cheng, Liangjun Lu, Hongmei Mo, William E. Kohlbrenner, Akhteruzzaman Molla, Warren M. Kati

Journal:

Antiviral Research

Year:

2004

Language:

english

File:

PDF, 302 KB

english, 2004

17

Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction

Hongmei Mo, Alex K. Konstantinidis, Kent D. Stewart, Tatyana Dekhtyar, Teresa Ng, Kerry Swift, Edmund D. Matayoshi, Warren Kati, William Kohlbrenner, Akhteruzzaman Molla

Journal:

Year:

2004

Language:

english

File:

PDF, 305 KB

english, 2004

18

GS4071 Is a Slow-Binding Inhibitor of Influenza Neuraminidase from Both A and B Strains

Warren M. Kati, Ayda S. Saldivar, Fariborz Mohamadi, Hing L. Sham, W.Graeme Laver, William E. Kohlbrenner

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 133 KB

english, 1998

19

The mode of inhibition of oxidative phosphorylation by efrapeptin (A23871): Measurement of substrate effects on rates of inactivation by a tight-binding inhibitor

William E. Kohlbrenner, Richard L. Cross

Journal:

Archives of Biochemistry and Biophysics

Year:

1979

Language:

english

File:

PDF, 934 KB

english, 1979

20

Heteronuclear three-dimensional NMR spectroscopy applied to CMP-KDO synthetase (27.5 kD)

Stephen W. Fesik, Robert T. Gampe Jr., Erik R.P. Zuiderweg, William E. Kohlbrenner, Debra Weigl

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 548 KB

english, 1989

21

Affinity purification of HIV-1 and HIV-2 proteases from recombinant E. coli strains using pepstatin-agarose

Judith Rittenhouse, Mary C. Turon, Rosalind J. Helfrich, Kathryn S. Albrecht, Debra Weigl, Robert L. Simmer, Federico Mordini, John Erickson, William E. Kohlbrenner

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 629 KB

english, 1990

22

Potent HIV-1 protease inhibitors with antiviral activities in vitro

Hing L. Sham, David A. Betebenner, Norman E. Wideburg, Ayda C. Saldivar, William E. Kohlbrenner, Sudthida Vasavanonda, Dale J. Kempf, Daniel W. Norbeck, Chen Zhao, Jacob J. Clement, John E. Erickson,

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 373 KB

english, 1991

23

Efficiency of phosphorylation of the Cyclobut-G (A-69992) enantiomers by HSV-1 thymidine kinase does not correlate with their anti-herpesvirus activity

William E. Kohlbrenner, Carole D. Carter, Stephen W. Fesik, Daniel W. Norbeck, John Erickson

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 494 KB

english, 1990

24

Lack of evidence for covalently-bound carbohydrates in energy-transducing ATPases from mitochondria, bacteria, and chloroplasts

Carlo M. Nalin, Richard L. Cross, John J. Lucas, William E. Kohlbrenner

Journal:

Year:

1979

Language:

english

File:

PDF, 489 KB

english, 1979

25

Pseudo-symmetrical difluoroketones: Highly potent and specific inhibitors of HIV-1 protease

Hing L. Sham, David A. Betebenner, Norman Wideburg, Ayda C. Saldivar, William E. Kohlbrenner, Adrienne Craig-Kennard, Sudthida Vasavanonda, Dale J. Kempf, Jacob J. Clement, John E. Erickson, Jacob J.

Journal:

Year:

1993

Language:

english

File:

PDF, 380 KB

english, 1993

26

Hepatitis C NS3 protease inhibition by peptidyl-α-ketoamide inhibitors: kinetic mechanism and structure

Yaya Liu, Vincent S. Stoll, Paul L. Richardson, Ayda Saldivar, Jeffrey L. Klaus, Akhteruzzaman Molla, William Kohlbrenner, Warren M. Kati

Journal:

Archives of Biochemistry and Biophysics

Year:

2004

Language:

english

File:

PDF, 301 KB

english, 2004

27

Anti-infectives

William E. Kohlbrenner, John F. Barrett

Journal:

Current Opinion in Pharmacology

Year:

2002

Language:

english

File:

PDF, 28 KB

english, 2002

28

Cardiac Surgical Delivery of the Sarcoplasmic Reticulum Calcium ATPase Rescues Myocytes in Ischemic Heart Failure

Fargnoli, Anthony S., Katz, Michael G., Yarnall, Charles, Isidro, Alice, Petrov, Michael, Steuerwald, Nury, Ghosh, Sriparna, Richardville, Kyle C., Hillesheim, Richard, Williams, Richard D., Kohlbrenn

Journal:

The Annals of Thoracic Surgery

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

29

Cationic lipids percentage and processing temperature are critical in designing siRNA lipid nanoparticles

Zhao, Xiaobin, Liu, Yemin, Song, Jingfeng, Yong, Hong, Li, Leiming, Shen, Yu, Hubbard, Robert D., Kohlbrenner, William E., Zhou, Ji, Cluff, Kevin D., Skoug, John W.

Journal:

Journal of Drug Targeting

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

30

Small-Sized Human Immunodeficiency Virus Type-1 Protease Inhibitors Containing Allophenylnorstatine to Explore the S 2 ′ Pocket

Hidaka, Koushi, Kimura, Tooru, Abdel-Rahman, Hamdy M., Nguyen, Jeffrey-Tri, McDaniel, Keith F., Kohlbrenner, William E., Molla, Akhteruzzaman, Adachi, Motoyasu, Tamada, Taro, Kuroki, Ryota, Katsuki, N

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.92 MB

english, 2009

31

Structure-based, C2 symmetric inhibitors of HIV protease

Kempf, Dale J., Norbeck, Daniel W., Codacovi, LynnMarie, Wang, Xiu Chun, Kohlbrenner, William E., Wideburg, Norman E., Paul, Deborah A., Knigge, Mark F., Vasavanonda, Sudthida

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 398 KB

english, 1990

32

Investigating the Origin of the Slow-Binding Inhibition of HCV NS3 Serine Protease by a Novel Substrate Based Inhibitor

Liu, Yaya, Saldivar, Ayda, Bess, Joshua, Solomon, Larry, Chen, Chih-Ming, Tripathi, Rakesh, Barrett, Leo, Richardson, Paul L., Molla, Akhteruzzaman, Kohlbrenner, William, Kati, Warren

Journal:

Year:

2003

Language:

english

File:

PDF, 115 KB

english, 2003

33

Corrigenda

Sham, Hing L., Wideburg, Norman E., Spanton, Stephen G., Kohlbrenner, William E., Betebenner, David A., Kempf, Dale J., Norbeck, Daniel W., Plattner, Jacob J., Erickson, John W., Shen, Gwo-Jenn, Wang,

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1991

Language:

english

File:

PDF, 71 KB

english, 1991

34

3-D structure of a mutant (Asp101 → Ser) of E.coli alkaline phosphatase with higher catalytic activity

Chen, Liqing, Neidhart, David, Kohlbrenner, William M., Mandecki, Wlodek, Bell, Sean, Sowadski, Janusz, Abad-Zapatero, Cele

Journal:

Protein Engineering Design and Selection

Year:

1992

Language:

english

File:

PDF, 569 KB

english, 1992

35

New Quinolone Compounds from Pseudonocardia sp. with Selective and Potent Anti-Helicobacter pylori Activity: Taxonomy of Producing Strain, Fermentation, Isolation, Structural Elucidation and Biological Activities.

DEKKER, KOEN A., INAGAKI, TAISUKE, GOOTZ, THOMAS D., HUANG, LIANG H., KOJIMA, YASUHIRO, KOHLBRENNER, WILLIAM E., MATSUNAGA, YASUE, MCGUIRK, PAUL R., NOMURA, ETSUKO, SAKAKIBARA, TATSUO, SAKEMI, SHINICH

Journal:

The Journal of Antibiotics

Year:

1998

Language:

english

File:

PDF, 1.13 MB

english, 1998

36

Pharmacokinetics and Cerebrospinal Fluid Concentrations of Cefixime in Infants and Young Children

Nahata, Milap C., Kohlbrenner, Veronika M., Barson, William J.

Journal:

Year:

1993

File:

PDF, 1.43 MB

1993

37

Aligning needs

Ford, Dennis, Kohlbrenner, William

Journal:

Bioentrepreneur

Year:

2016

Language:

english

File:

PDF, 578 KB

english, 2016